L-(?)-3-Phenyllactic acid

CAS No. 20312-36-1

L-(?)-3-Phenyllactic acid( (S)-2-Hydroxy-3-phenylpropanoic acid )

Catalog No. M20030 CAS No. 20312-36-1

L-3-Phenyllactic acid (or PLA) is a chiral aromatic compound involved in phenylalanine metabolism. It is likely produced from phenylpyruvate via the action of lactate dehydrogenase.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    L-(?)-3-Phenyllactic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    L-3-Phenyllactic acid (or PLA) is a chiral aromatic compound involved in phenylalanine metabolism. It is likely produced from phenylpyruvate via the action of lactate dehydrogenase.
  • Description
    L-3-Phenyllactic acid (or PLA) is a chiral aromatic compound involved in phenylalanine metabolism. It is likely produced from phenylpyruvate via the action of lactate dehydrogenase. The D-form of this organic acid is typically derived from bacterial sources while the L-form is almost certainly endogenous. Levels of phenyllactate are normally very low in blood or urine. High levels of PLA in the urine or blood are often indicative of phenylketonuria (PKU) and hyperphenylalaninemia (HPA). PKU is due to lack of the enzyme phenylalanine hydroxylase (PAH) so that phenylalanine is converted not to tyrosine but to phenylpyruvic acid (a precursor of phenylacetate).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    (S)-2-Hydroxy-3-phenylpropanoic acid
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    20312-36-1
  • Formula Weight
    166.17
  • Molecular Formula
    C9H10O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:200 mM
  • SMILES
    O[C@@H](Cc1ccccc1)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tekewe A et al. Development and validation of HPLC method for the resolution of drug intermediates: DL-3-Phenyllactic acid DL-O-acetyl-3-phenyllactic acid and (+/-)-mexiletine acetamide enantiomers. Talanta. 2008 Mar 15;75(1):239-45.
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