Cholesteryl linoleate
CAS No. 604-33-1
Cholesteryl linoleate( CE(18:2(9Z12Z)) | Cholesterol Linoleate | Linoleic Acid cholesteryl ester )
Catalog No. M20009 CAS No. 604-33-1
Cholesteryl linoleate is a cholesterol ester found in LDL. Cholesteryl linoleate is transferred to the plasma membrane of macrophages and CHO cells expressing 15-lipoxygenase (15-LO) via LDL receptor-related protein (LRP) where it undergoes oxidation to form cholesteryl linoleate hydroperoxides.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | In Stock |
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| 200MG | 32 | In Stock |
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| 500MG | 49 | In Stock |
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| 1G | 72 | In Stock |
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Biological Information
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Product NameCholesteryl linoleate
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NoteResearch use only, not for human use.
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Brief DescriptionCholesteryl linoleate is a cholesterol ester found in LDL. Cholesteryl linoleate is transferred to the plasma membrane of macrophages and CHO cells expressing 15-lipoxygenase (15-LO) via LDL receptor-related protein (LRP) where it undergoes oxidation to form cholesteryl linoleate hydroperoxides.
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DescriptionCholesteryl linoleate is a cholesterol ester found in LDL. Cholesteryl linoleate is transferred to the plasma membrane of macrophages and CHO cells expressing 15-lipoxygenase (15-LO) via LDL receptor-related protein (LRP) where it undergoes oxidation to form cholesteryl linoleate hydroperoxides.
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In Vitro——
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In Vivo——
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SynonymsCE(18:2(9Z12Z)) | Cholesterol Linoleate | Linoleic Acid cholesteryl ester
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number604-33-1
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Formula Weight649.1
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Molecular FormulaC45H76O2
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Purity>98% (HPLC)
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SolubilityChloroform: 10 mg/mL;DMSO: Soluble
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SMILESCCCCC\C=C/C\C=C/CCCCCCCC(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@]4(C)[C@H](CC[C@H]4[C@@H]3CC=C2C1)[C@H](C)CCCC(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Dieugenol
Dieugenol is a neolignan that has been found in N. leucantha and has antioxidative and antiprotozoal activities. It inhibits the formation of thiobarbituric acid reactive substances (TBARS) and scavenges superoxide anions, but not hydroxyl radicals, in cell-free assays. It has anti-trypanosomal activity against T. cruzi amastigotes and trypomastigotes (IC50s=15.1 and 11.5 μM, respectively) but is cytotoxic to NCTC L-929 fibroblasts with a 50% cytotoxic concentration (CC50) value of 58.2 μM.2 Dieugenol (15 μM) disrupts the integrity of the T. cruzi trypomastigote plasma membrane but does not induce the production of reactive oxygen species (ROS) in trypomastigotes or LPS-stimulated and unstimulated isolated mouse peritoneal macrophages.
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