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SR3335
CAS No. 293753-05-6
SR3335( ML 176 )
Catalog No. M19947 CAS No. 293753-05-6
SR 3335 is a selective inverse agonist of RORα competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (Ki: 220 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 75 | In Stock |
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| 5MG | 68 | In Stock |
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| 10MG | 122 | In Stock |
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| 25MG | 245 | In Stock |
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| 50MG | 384 | In Stock |
|
| 100MG | 616 | In Stock |
|
| 200MG | 861 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSR3335
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NoteResearch use only, not for human use.
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Brief DescriptionSR 3335 is a selective inverse agonist of RORα competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (Ki: 220 nM).
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DescriptionSR 3335 is a selective inverse agonist of RORα competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (Ki: 220 nM).
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In Vitro——
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In Vivo——
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SynonymsML 176
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PathwayNuclear Receptor/Transcription Factor
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TargetROR
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RecptorRORα
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Research Area——
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Indication——
Chemical Information
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CAS Number293753-05-6
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Formula Weight405.34
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Molecular FormulaC13H9F6NO3S2
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Purity>98% (HPLC)
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SolubilityEthanol: 30 mg/mL;DMSO: 40 mg/mL
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SMILESOC(c1ccc(NS(=O)(=O)c2cccs2)cc1)(C(F)(F)F)C(F)(F)F
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Chemical NameN-[4-[222-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-2-thiophenesulfonamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kumar N et al. Identification of SR3335 (ML-176): a synthetic RORα selective inverse agonist. ACS Chem Biol. 2011 Mar 18;6(3):218-22.
molnova catalog
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