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SRT 1720 dihydrochloride

CAS No. ——

SRT 1720 dihydrochloride( —— )

Catalog No. M19917 CAS No. ——

SRT 1720 is a selective activator of SIRT1 (EC1.5: 0.16 μM) and shows less potent activities on SIRT2 (EC1.5: 37 μM) and SIRT3 (EC1.5: 300 μM).

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    SRT 1720 dihydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    SRT 1720 is a selective activator of SIRT1 (EC1.5: 0.16 μM) and shows less potent activities on SIRT2 (EC1.5: 37 μM) and SIRT3 (EC1.5: 300 μM).
  • Description
    SRT 1720 is a selective activator of SIRT1 (EC1.5: 0.16 μM) and shows less potent activities on SIRT2 (EC1.5: 37 μM) and SIRT3 (EC1.5: 300 μM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    Sirtuin
  • Recptor
    SIRT1|SIRT2
  • Research Area
    Cancer
  • Indication
    Amyotrophic lateral sclerosis; Cancer; Chronic obstructive pulmonary disease; Huntington's disease; Inflammation

Chemical Information

  • CAS Number
    ——
  • Formula Weight
    542.48
  • Molecular Formula
    C25H25Cl2N7OS
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 80 mg/mL;Water: 10 mg/mL
  • SMILES
    Cl.Cl.O=C(Nc1ccccc1-c1cn2c(CN3CCNCC3)csc2n1)c1cnc2ccccc2n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Milne JC et al. Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature. 2007 Nov 29;450(7170):712-6.
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