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SM 16
CAS No. 614749-78-9
SM 16( —— )
Catalog No. M19909 CAS No. 614749-78-9
SM 16 is a ALK5/ALK4 kinase inhibitor (Ki: 10/1.5 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 80 | In Stock |
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| 10MG | 140 | In Stock |
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| 25MG | 250 | In Stock |
|
| 50MG | 405 | In Stock |
|
| 100MG | 597 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSM 16
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NoteResearch use only, not for human use.
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Brief DescriptionSM 16 is a ALK5/ALK4 kinase inhibitor (Ki: 10/1.5 nM).
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DescriptionSM 16 is a ALK5/ALK4 kinase inhibitor (Ki: 10/1.5 nM).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetALK
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RecptorALK4| ALK5
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Research AreaCancer
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IndicationCancer
Chemical Information
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CAS Number614749-78-9
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Formula Weight430.5
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Molecular FormulaC25H26N4O3
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Purity>98% (HPLC)
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SolubilityDMSO: 60 mg/mL
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SMILESCc1cccc(n1)-c1[nH]c(nc1-c1ccc2OCOc2c1)C12CCC(CC1)(CC2)C(N)=O
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Chemical Name4-[4-(13-Benzodioxol-5-yl)-5-(6-methyl-2-pyridinyl)-1H-imidazol-2-yl]-bicyclo[2.2.2]octane-1-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Suzuki E et al. A novel small-molecule inhibitor of transforming growth factor beta type I receptor kinase (SM16) inhibits murine mesothelioma tumor growth in vivo and prevents tumor recurrence after surgical resection. Cancer Res. 2007 Mar 1;67(5):2351-9.
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