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Neticonazole Hydrochloride
CAS No. 130773-02-3
Neticonazole Hydrochloride( —— )
Catalog No. M19872 CAS No. 130773-02-3
Neticonazole Hydrochloride is an imidazole antifungal for the treatment of fungal skin infections. Neticonazole is reported as a potent exosome inhibitor which can block the activity of exosomes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 50 | In Stock |
|
| 50MG | 73 | In Stock |
|
| 100MG | 125 | In Stock |
|
| 200MG | 186 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNeticonazole Hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionNeticonazole Hydrochloride is an imidazole antifungal for the treatment of fungal skin infections. Neticonazole is reported as a potent exosome inhibitor which can block the activity of exosomes.
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DescriptionNeticonazole Hydrochloride is an imidazole antifungal for the treatment of fungal skin infections. Neticonazole is reported as a potent exosome inhibitor which can block the activity of exosomes.
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In VitroWestern Blot Analysis Cell Line:C4-2B cells Concentration:10 μM Incubation Time:48 hours Result:Decreased the levels of both Alix and Rab27a, and significantly decreased nSMase2 levels.
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In VivoAnimal Model:Male C57BL/6 mice (8 weeks old) given ampicillin, neomycin, metronidazole and vancomycin, and injected with SW480 cellsDosage:1 ng/kg, 10 ng/kg and 100 ng/kg Administration:Oral gavage; daily; for 15 days Result:Significantly improved the survival of IDB mice with CRC xenograft tumors.
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Synonyms——
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PathwayMicrobiology/Virology
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TargetAntifungal
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RecptorAntifungal
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Research AreaCancer
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IndicationPCa(prostatic Cancer)
Chemical Information
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CAS Number130773-02-3
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Formula Weight338.9
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Molecular FormulaC17H22N2OS.HCl
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Purity>98% (HPLC)
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SolubilityDMSO: 50 mg/mL
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SMILESCl.CCCCCOc1ccccc1\C(=C/SC)n1ccnc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Datta A et al. High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer. Sci Rep. 2018 May 25;8(1):8161.
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