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α-Ketoglutaric acid sodium salt
CAS No. 22202-68-2
α-Ketoglutaric acid sodium salt( 2-oxoglutarate monobasic | Oxoglutaric acid | AKG )
Catalog No. M19760 CAS No. 22202-68-2
alpha-Ketoglutarate is a key molecule in the TCA cycle. It can be produced from glutamate by oxidative deamination via glutamate dehydrogenase and as a product of pyridoxal phosphate-dependent transamination reactions (mediated by branched-chain amino acid transaminases) in which glutamate is a common amino donor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | 28 | In Stock |
|
| 500MG | 41 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Nameα-Ketoglutaric acid sodium salt
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NoteResearch use only, not for human use.
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Brief Descriptionalpha-Ketoglutarate is a key molecule in the TCA cycle. It can be produced from glutamate by oxidative deamination via glutamate dehydrogenase and as a product of pyridoxal phosphate-dependent transamination reactions (mediated by branched-chain amino acid transaminases) in which glutamate is a common amino donor.
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Descriptionalpha-Ketoglutarate is a key molecule in the TCA cycle(PMID: 26759695 ). It can be produced from glutamate by oxidative deamination via glutamate dehydrogenase and as a product of pyridoxal phosphate-dependent transamination reactions (mediated by branched-chain amino acid transaminases) in which glutamate is a common amino donor.
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In Vitro2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) has other physiological capabilities including reduction of ammonia level formed in the lung and general ammonia detoxification, protective role against lipid peroxidation and neuroprotective effect against cyanide poisoning.2-Ketoglutaric acid Sodium acts as precursor for the synthesis of amino acids and nucleotides.
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In Vivo——
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Synonyms2-oxoglutarate monobasic | Oxoglutaric acid | AKG
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number22202-68-2
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Formula Weight168.08
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Molecular FormulaC5H5NaO5
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILES[Na+].OC(=O)CCC(=O)C([O-])=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Wu N et al. Alpha-Ketoglutarate: Physiological Functions and Applications. Biomol Ther (Seoul). 2016 Jan;24(1):1-8.
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