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Erucic acid
CAS No. 112-86-7
Erucic acid( cis-13-docosenoic acid | 13(Z)-Docosenoic Acid | Prifac 2990 )
Catalog No. M19744 CAS No. 112-86-7
Increased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 46 | In Stock |
|
| 50MG | 31 | In Stock |
|
| 100MG | 42 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 93 | In Stock |
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| 1G | 135 | In Stock |
|
Biological Information
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Product NameErucic acid
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NoteResearch use only, not for human use.
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Brief DescriptionIncreased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression.
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DescriptionIncreased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression (PMID: 16581239 ). Erucic acid is broken down long-chain acyl-coenzyme A (CoA) dehydrogenase which is produced in the liver. This enzyme breaks this long chain fatty acid into shorter-chain fatty acids. human infants have relatively low amounts of this enzyme and because of this babies should not be given foods high in erucic acid. Erucic acid is found to be associated with isovaleric acidemia which is an inborn error of metabolism.
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In Vitro——
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In VivoErucic acid (oral administration; 3 mg/kg) enhances the phosphorylation level of PI3K, PKCζ, ERK, CREB and Akt in the hippocampus compared with that in the vehicle-treated control group. Animal Model:Normal na?ve mice Dosage:3 mg/kg Administration:Oral administration; 3 mg/kg Result:Enhanced the phosphorylation level of PI3K, PKCζ, ERK, CREB and Akt in the hippocampus.
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Synonymscis-13-docosenoic acid | 13(Z)-Docosenoic Acid | Prifac 2990
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PathwayProteasome/Ubiquitin
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TargetEndogenous Metabolite
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RecptorHuman Endogenous Metabolite
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Research Area——
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Indication——
Chemical Information
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CAS Number112-86-7
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Formula Weight338.57
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Molecular FormulaC22H42O2
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Purity>98% (HPLC)
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SolubilityDMSO:197.9 mM
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SMILESCCCCCCCC\C=C/CCCCCCCCCCCC(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Aubourg P Adamsbaum C Lavallardrousseau M C et al. A two-year trial of oleic and erucic acids ("Lorenzo's oil") as treatment for adrenomyeloneuropathy.[J]. New England Journal of Medicine 1993 329(11):745.
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