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Home - Products - Proteasome/Ubiquitin - Endogenous Metabolite - L-Methionine

L-Methionine

CAS No. 63-68-3

L-Methionine( L-Methionin | L(-)-Methionin )

Catalog No. M19651 CAS No. 63-68-3

L-Methionine is the L-isomer of Methionine an essential amino acid for human development. Methionine acts as a hepatoprotectant.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    L-Methionine
  • Note
    Research use only, not for human use.
  • Brief Description
    L-Methionine is the L-isomer of Methionine an essential amino acid for human development. Methionine acts as a hepatoprotectant.
  • Description
    L-Methionine is the L-isomer of Methionine an essential amino acid for human development. Methionine acts as a hepatoprotectant.
  • In Vitro
    Cell Proliferation Assay Cell Line:BXPC-3, HPAC Concentration:5 mg/mL Incubation Time:7 or 3 days Result:Reduced growth of BXPC-3 cells by 31 and 32%, respectively. Reduced growth of HPAC cells by 35% and 18%, respectively. Reduced S to G2 transition in BXPC-3 cells and intervened in both G1–S and S–G2 transitions in HPAC cells. Increased late cell apoptosis at a percentage of 76% in BXPC-3 cells.Western Blot Analysis Cell Line:ECV304 Concentration:0.3, 1, 3, 5, 10 mM Incubation Time:24 h Result:Increased the level of HO-1 protein up to 9.5-fold and the HO-1 activity.
  • In Vivo
    Animal Model:Male Wistar rats (body weight 70-80 g) Dosage:215,268.8, 322.5, 430 mg/kg Administration:p.o.Result:Reduced the hepatic ROS levels and the hepatic MDA contents. Increased the hepatic T-AOC, CAT and T-SOD. Increased the hepatic activity of GCL, GR, GST and GPx.
  • Synonyms
    L-Methionin | L(-)-Methionin
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Endogenous Metabolite
  • Research Area
    Metabolic Disease
  • Indication
    Nutritional fortifier acute hepatitis cirrhosis

Chemical Information

  • CAS Number
    63-68-3
  • Formula Weight
    149.21
  • Molecular Formula
    C5H11NO2S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10uM;Water:Soluble
  • SMILES
    CSCC[C@H](N)C(O)=O
  • Chemical Name
    L-methionine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Sreekumar A Poisson L M Rajendiran T M et al. Corrigendum: Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression[J]. Nature 2009 457(7231):910-914.
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