L-Dihydroorotic acid

Research use only, not for human use.

L-Dihydroorotic acid also known as (S)-45-dihydroorotate or dihydro-L-orotate belongs to the class of organic compounds known as alpha amino acids and derivatives.

L-Dihydroorotic acid also known as (S)-45-dihydroorotate or dihydro-L-orotate belongs to the class of organic compounds known as alpha amino acids and derivatives. Within the cell L-dihydroorotic acid is primarily located in the cytoplasm and mitochondria. L-Dihydroorotic acid exists in all eukaryotes ranging from yeast to humans. L-Dihydroorotic acid participates in a number of enzymatic reactions. In particular L-Dihydroorotic acid can be biosynthesized from ureidosuccinic acid; which is catalyzed by the enzyme cad protein. In addition L-Dihydroorotic acid and quinone can be converted into orotic acid; which is mediated by the enzyme dihydroorotate dehydrogenase (quinone) mitochondrial. In humans L-dihydroorotic acid is involved in the pyrimidine metabolism pathway. L-Dihydroorotic acid is also involved in several metabolic disorders some of which include UMP synthase deficiency (orotic aciduria) the mngie (mitochondrial neurogastrointestinal encephalopathy) pathway Beta ureidopropionase deficiency and dihydropyrimidinase deficiency.

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Others

Other Targets

Others

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5988-19-2

158.11

C5H6N2O4

>98% (HPLC)

DMSO:196.1 mM

OC(=O)[C@@H]1CC(=O)NC(=O)N1

(S)-26-dioxohexahydropyrimidine-4-carboxylic acid

(-20℃)

With Ice Pack

≥ 2 years