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4-Methylcatechol
CAS No. 452-86-8
4-Methylcatechol( p-Methylcatechol | 34-Dihydroxytoluene | Homocatechol | 4-methylbenzene-12-diol )
Catalog No. M19606 CAS No. 452-86-8
4-methylcatechol is a metabolite of homoprotocatechuic acid. It is both a substrate and a suicide inhibitor of Catechol 23-dioxygenase. 4-methylcatechol is known to induce the production of brain-derived neurotrophic factor (BDNF). Recent studies have suggested that a lack of brain-derived neurotrophic factor (BDNF) in the limbic system may cause neuropathic pain.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 45 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product Name4-Methylcatechol
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NoteResearch use only, not for human use.
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Brief Description4-methylcatechol is a metabolite of homoprotocatechuic acid. It is both a substrate and a suicide inhibitor of Catechol 23-dioxygenase. 4-methylcatechol is known to induce the production of brain-derived neurotrophic factor (BDNF). Recent studies have suggested that a lack of brain-derived neurotrophic factor (BDNF) in the limbic system may cause neuropathic pain.
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Description4-methylcatechol is a metabolite of homoprotocatechuic acid. It is both a substrate and a suicide inhibitor of Catechol 23-dioxygenase. 4-methylcatechol is known to induce the production of brain-derived neurotrophic factor (BDNF). Recent studies have suggested that a lack of brain-derived neurotrophic factor (BDNF) in the limbic system may cause neuropathic pain.
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In Vitro——
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In Vivo——
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Synonymsp-Methylcatechol | 34-Dihydroxytoluene | Homocatechol | 4-methylbenzene-12-diol
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PathwayOthers
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TargetOther Targets
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RecptorCatechol 23-Dioxygenase
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Research AreaNeurological Disease
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IndicationDiabetic neuropathies; Neuropathic pain
Chemical Information
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CAS Number452-86-8
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Formula Weight124.14
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Molecular FormulaC7H8O2
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM;Water: Soluble;Ethanol: Soluble
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SMILESCc1ccc(O)c(O)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Okuta A et al. Construction of chimeric catechol 23-dioxygenase exhibiting improved activity against the suicide inhibitor 4-methylcatechol. Appl Environ Microbiol. 2004 Mar;70(3):1804-10.
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