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2'-Deoxyguanosine monohydrate

CAS No. 312693-72-4

2'-Deoxyguanosine monohydrate( Guanine-2'-deoxyriboside )

Catalog No. M19592 CAS No. 312693-72-4

Deoxyguanosine is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine but with one oxygen atom removed. It is a nucleoside component of DNA. Deoxyguanosine can be converted to 8-hydroxy-deoxyguanosine (8-OHdG) due to hydroxyl radical attack at the C8 of guanine.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    2'-Deoxyguanosine monohydrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Deoxyguanosine is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine but with one oxygen atom removed. It is a nucleoside component of DNA. Deoxyguanosine can be converted to 8-hydroxy-deoxyguanosine (8-OHdG) due to hydroxyl radical attack at the C8 of guanine.
  • Description
    Deoxyguanosine is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine but with one oxygen atom removed. It is a nucleoside component of DNA. Deoxyguanosine can be converted to 8-hydroxy-deoxyguanosine (8-OHdG) due to hydroxyl radical attack at the C8 of guanine. 8-OHdG is a sensitive marker of the DNA damage This damage if left unrepaired has been proposed to contribute to mutagenicity and cancer promotion.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Guanine-2'-deoxyriboside
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    312693-72-4
  • Formula Weight
    285.26
  • Molecular Formula
    C10H15N5O5
  • Purity
    >98% (HPLC)
  • Solubility
    1 M NH4OH: 50 mg/mL
  • SMILES
    O.Nc1nc(=O)c2ncn([C@H]3C[C@H](O)[C@@H](CO)O3)c2[nH]1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Gao K et al. The citrus flavonoid naringenin stimulates DNA repair in prostate cancer cells. J Nutr Biochem. 2006 Feb;17(2):89-95. Epub 2005 Jun 20.
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