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Tomatine

CAS No. 17406-45-0

Tomatine( lycopersicin )

Catalog No. M19426 CAS No. 17406-45-0

An antiproliferatve agent of breast adenocarcinoma cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 88 In Stock
2MG 29 In Stock
5MG 46 In Stock
10MG 77 In Stock
25MG 141 In Stock
50MG 204 In Stock
100MG 303 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Tomatine
  • Note
    Research use only, not for human use.
  • Brief Description
    An antiproliferatve agent of breast adenocarcinoma cells.
  • Description
    Tomatine is a glycoalkaloid found in the tomato plant (Lycopersicon esculentum Mill.). Tomatine elicits neurotoxicity in RIP1 kinase and caspase-independent manner. Tomatine promotes the upregulation of nuclear apoptosis inducing factor (AIF) in neuroblastoma cells. Tomatine also inhibits 20S proteasome activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    lycopersicin
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    17406-45-0
  • Formula Weight
    1034.2
  • Molecular Formula
    C50H83NO21
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:96.7 mM
  • SMILES
    C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC[C@H]5C[C@H](CC[C@]5(C)[C@H]4CC[C@]23C)O[C@@H]2O[C@H](CO)[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O[C@@H]4OC[C@@H](O)[C@H](O)[C@H]4O)[C@H]3O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)O[C@@]11CC[C@H](C)CN1
  • Chemical Name
    (2S3R4S5S6R)-2-(((2S3R4S5R6R)-2-(((2R3R4R5R6R)-45-dihydroxy-2-(hydroxymethyl)-6-(((2aS4S5'S6aS6bS8aS8bR9S10S11aS12aS12bR)-5'6a8a9-tetramethyloctadecahydrospiro[naphtho[2'1':45]indeno[21-b]furan-102'-piperidin]-4-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-5-hydroxy-6-(hydroxymethyl)-4-(((2S3R4S5R)-345-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-345-triol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Bretschneider A. et al. Know your ABCs: Characterization and gene expression dynamics of ABC transporters in the polyphagous herbivore Helicoverpa armigera. Insect Biochem Mol Biol. 2016 May;72:1-9.
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