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Tomatine
CAS No. 17406-45-0
Tomatine( lycopersicin )
Catalog No. M19426 CAS No. 17406-45-0
An antiproliferatve agent of breast adenocarcinoma cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 88 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 46 | In Stock |
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| 10MG | 77 | In Stock |
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| 25MG | 141 | In Stock |
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| 50MG | 204 | In Stock |
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| 100MG | 303 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTomatine
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NoteResearch use only, not for human use.
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Brief DescriptionAn antiproliferatve agent of breast adenocarcinoma cells.
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DescriptionTomatine is a glycoalkaloid found in the tomato plant (Lycopersicon esculentum Mill.). Tomatine elicits neurotoxicity in RIP1 kinase and caspase-independent manner. Tomatine promotes the upregulation of nuclear apoptosis inducing factor (AIF) in neuroblastoma cells. Tomatine also inhibits 20S proteasome activity.
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In Vitro——
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In Vivo——
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Synonymslycopersicin
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number17406-45-0
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Formula Weight1034.2
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Molecular FormulaC50H83NO21
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Purity>98% (HPLC)
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SolubilityDMSO:96.7 mM
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SMILESC[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC[C@H]5C[C@H](CC[C@]5(C)[C@H]4CC[C@]23C)O[C@@H]2O[C@H](CO)[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O[C@@H]4OC[C@@H](O)[C@H](O)[C@H]4O)[C@H]3O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)O[C@@]11CC[C@H](C)CN1
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Chemical Name(2S3R4S5S6R)-2-(((2S3R4S5R6R)-2-(((2R3R4R5R6R)-45-dihydroxy-2-(hydroxymethyl)-6-(((2aS4S5'S6aS6bS8aS8bR9S10S11aS12aS12bR)-5'6a8a9-tetramethyloctadecahydrospiro[naphtho[2'1':45]indeno[21-b]furan-102'-piperidin]-4-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-5-hydroxy-6-(hydroxymethyl)-4-(((2S3R4S5R)-345-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-345-triol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Bretschneider A. et al. Know your ABCs: Characterization and gene expression dynamics of ABC transporters in the polyphagous herbivore Helicoverpa armigera. Insect Biochem Mol Biol. 2016 May;72:1-9.
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