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MS049 2HCl

CAS No. ——

MS049 2HCl ( —— )

Catalog No. M19312 CAS No. ——

MS049 is a potent and selective inhibitor of PRMT4 (IC50 = 34 nM) and PRMT6 (IC50 = 43 nM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

MS049 2HCl
Note

Research use only, not for human use.
Brief Description

MS049 is a potent and selective inhibitor of PRMT4 (IC50 = 34 nM) and PRMT6 (IC50 = 43 nM).
Description

MS049 is a potent and selective inhibitor of PRMT4 (IC50 = 34 nM) and PRMT6 (IC50 = 43 nM). It is less active against additional type I PRMTs (IC50s = >130, >220, and 1.6 μM for PRMT1, PRMT3, and PRMT8, respectively) and displays no inhibition against type II or type III PRMTs nor any additional methyltransferases or nonepigenetic targets tested.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

PRMT4| PRMT6
Research Area

——
Indication

——

Chemical Information

CAS Number

——
Formula Weight

321.28
Molecular Formula

C15H26Cl2N2O
Purity

>98% (HPLC)
Solubility

——
SMILES

Cl.Cl.CNCCN1CCC(CC1)OCc2ccccc2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Shen Y, etal. Journal of Medicinal Chemistry, 2016, 59(19):9124-9139.

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