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PHA767491 HCl
CAS No. 942425-68-5
PHA767491 HCl( CAY-10572 hydrochloride )
Catalog No. M19277 CAS No. 942425-68-5
PHA-767491 is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 46 | In Stock |
|
| 5MG | 41 | In Stock |
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| 10MG | 58 | In Stock |
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| 25MG | 93 | In Stock |
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| 50MG | 133 | In Stock |
|
| 100MG | 219 | In Stock |
|
| 200MG | 324 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePHA767491 HCl
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NoteResearch use only, not for human use.
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Brief DescriptionPHA-767491 is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM).
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DescriptionPHA-767491 is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM). It has ~20-fold selectivity against GSK3-β and CDK1/2, 50-fold selectivity against CDK5 and MK2, 100-fold selectivity against CHK2 and PLK1.
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In Vitro——
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In Vivo——
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SynonymsCAY-10572 hydrochloride
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PathwayEndocrinology/Hormones
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TargetReductase
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RecptorCdk1| Cdk2| Cdk9| Cdc7| GSK-3β
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number942425-68-5
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Formula Weight213.24
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Molecular FormulaC12H11N3O
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Purity>98% (HPLC)
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SolubilityDMSO : 17.33 mg/mL 69.40 mM
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SMILESCl.O=C1NCCc2nc(cc12)c3ccncc3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Montagnoli A, et al. Nat Chem Biol, 2008, 4(6), 357-365.
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