Cycloastragenol( Cyclogalegigenin | Astramembrangenin )

Catalog No. M19171 CAS No. 84605-18-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Cycloastragenol
Note

Research use only, not for human use.
Brief Description

Cycloastragenol is able to elongate telomeres, resulting in increased lifespan of the animals.
Description

Cycloastragenol is a molecule isolated from various species of Astragalus that is purported to have telomerase activation activity. A single in vitro study done in 2009 led to claims that cycloastragenol may activate telomerase, leading to controversial claims for its role in reducing the effects of aging.
In Vitro

——
In Vivo

——
Synonyms

Cyclogalegigenin | Astramembrangenin
Pathway

GPCR/G Protein
Target

Dopamine Receptor
Recptor

Telomerase
Research Area

Others-Field
Indication

——

CAS Number

84605-18-5
Formula Weight

490.72
Molecular Formula

C30H50O5
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 100 mg/mL 203.78 mM; H2O : < 0.1 mg/mL
SMILES

[C@]12([C@](CC[C@@]34[C@]5(CC[C@@H](C([C@@H]5[C@H](C[C@@H]13)O)(C)C)O)C4)([C@H]([C@@H](C2)O)[C@]1(O[C@H](CC1)C(C)(C)O)C)C)C
Chemical Name

(3β,6α,9β,16β,20R,24S)-20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol

1. de Jesus BB, et al. Aging Cell. 2011, 10 (4): 604–21.

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