Cart
sales@molnova.com
Enalapril Maleate
CAS No. 76095-16-4
Enalapril Maleate( MK-421 (maleate) )
Catalog No. M19083 CAS No. 76095-16-4
Enalapril Maleate, an angiotensin-converting enzyme (ACE) inhibitor, is utilized in the treatment of hypertension, chronic heart failure , and diabetic nephropathy.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | 39 | In Stock |
|
Biological Information
-
Product NameEnalapril Maleate
-
NoteResearch use only, not for human use.
-
Brief DescriptionEnalapril Maleate, an angiotensin-converting enzyme (ACE) inhibitor, is utilized in the treatment of hypertension, chronic heart failure , and diabetic nephropathy.
-
DescriptionEnalapril Maleate, an angiotensin-converting enzyme (ACE) inhibitor, is utilized in the treatment of hypertension, chronic heart failure , and diabetic nephropathy.(In Vivo):Enalapril (MK-421) is a prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to enalaprilat following oral administration. Enalapril (MK-421) is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Enalapril may be used to treat essential or renovascular hypertension and symptomatic congestive heart failure.
-
In Vitro——
-
In VivoEnalapril (MK-421) is a prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to enalaprilat following oral administration. Enalapril (MK-421) is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Enalapril may be used to treat essential or renovascular hypertension and symptomatic congestive heart failure.
-
SynonymsMK-421 (maleate)
-
PathwayProteasome/Ubiquitin
-
TargetEndogenous Metabolite
-
RecptorACE
-
Research AreaCardiovascular Disease
-
Indication——
Chemical Information
-
CAS Number76095-16-4
-
Formula Weight492.52
-
Molecular FormulaC20H28N2O5·C4H4O4
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 50 mg/mL 101.52 mM H2O : 33.33 mg/mL67.67 mM
-
SMILESOC(=O)/C=C\C(=O)O.N1(C(=O)[C@@H](N[C@H](C(=O)OCC)CCc2ccccc2)C)[C@H](C(=O)O)CCC1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Vlasses PH, et al. Clin Pharm,1985, 4(1), 27-40.
molnova catalog
related products
-
3-Ureidopropionic ac...
Ureidopropionic acid is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase.
-
cis-4-Hydroxy-L-prol...
cis-4-Hydroxy-L-proline is an inhibitor of the synthesis and extracellular deposition of collagen. cis-4-Hydroxy-L-proline could inhibit fibroblast growth by preventing the deposition of triple-helical collagen on the cell layer.
-
L-Homocystine
Homocystine is the double-bonded form of homocysteine but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Increasing evidence supports a role for an elevation of homocysteine in schizophrenia.
