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Praeruptorin A

CAS No. 73069-27-9

Praeruptorin A( —— )

Catalog No. M19050 CAS No. 73069-27-9

Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Praeruptorin A
  • Note
    Research use only, not for human use.
  • Brief Description
    Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis.
  • Description
    Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    CAM
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    73069-27-9
  • Formula Weight
    386.4
  • Molecular Formula
    C21H22O7
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 33.33 mg/mL (86.26 mM)
  • SMILES
    C/C=C(/C)\C(=O)O[C@H]1[C@H](c2c(ccc3c2oc(=O)cc3)OC1(C)C)OC(=O)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Xu Z1, Wang X, Dai Y, Kong L, et al..Chem Biol Interact. 2010 Jul 30;186(2):239-46.
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