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Praeruptorin A
CAS No. 73069-27-9
Praeruptorin A( —— )
Catalog No. M19050 CAS No. 73069-27-9
Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 29 | In Stock |
|
| 10MG | 38 | In Stock |
|
| 25MG | 65 | In Stock |
|
| 50MG | 100 | In Stock |
|
| 100MG | 166 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePraeruptorin A
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NoteResearch use only, not for human use.
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Brief DescriptionPraeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis.
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DescriptionPraeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorCAM
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number73069-27-9
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Formula Weight386.4
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Molecular FormulaC21H22O7
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 33.33 mg/mL (86.26 mM)
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SMILESC/C=C(/C)\C(=O)O[C@H]1[C@H](c2c(ccc3c2oc(=O)cc3)OC1(C)C)OC(=O)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Xu Z1, Wang X, Dai Y, Kong L, et al..Chem Biol Interact. 2010 Jul 30;186(2):239-46.
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