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Linderalactone
CAS No. 728-61-0
Linderalactone( Linderalactone )
Catalog No. M19045 CAS No. 728-61-0
Linderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48 μg/mL.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 104 | In Stock |
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| 5MG | 76 | In Stock |
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| 10MG | 122 | In Stock |
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| 25MG | 208 | In Stock |
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| 50MG | 303 | In Stock |
|
| 100MG | 452 | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameLinderalactone
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NoteResearch use only, not for human use.
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Brief DescriptionLinderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48 μg/mL.
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DescriptionLinderalactone is an NSAID isolated from Lindera aggregata.
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In VitroCell Viability Assay Cell Line:Lung cancer A549 cells Concentration:0 μM, 1.6 μM, 3.2 μM, 6.25 μM, 12.5 μM, 25 μM, 50 μM, 100 μM Incubation Time:24 hours Result:Inhibited the growth of A549 cells concentration-dependently.Apoptosis Analysis Cell Line:Lung cancer A549 cells Concentration:7.5 μM, 15 μM, 30 μM Incubation Time:Result:Induced apoptosis in A549 cells in a dose-dependent manner. Cell Cycle Analysis Cell Line:Lung cancer A549 cells Concentration:7.5 μM, 15 μM, 30 μM Incubation Time:24 hours Result:Induced G2/M cell cycle arrest.Western Blot Analysis Cell Line:Lung cancer A549 cells Concentration:7.5 μM, 15 μM, 30 μM Incubation Time:Result:Inhibited the JAK/STAT pathway in A549 cells.
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In Vivo——
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SynonymsLinderalactone
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number728-61-0
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Formula Weight244.29
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Molecular FormulaC15H16O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 33.33 mg/mL (136.44 mM)
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SMILESCC1=CCCC2=CC(C3=C(C1)OC=C3C)OC2=O
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Chemical Name(R,7Z,10E)-3,11-dimethyl-4,8,9,12-tetrahydro-6H-4,7-(metheno)furo[3,2-c][1]oxacycloundecin-6-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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