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Mitoxantrone

CAS No. 65271-80-9

Mitoxantrone( mitozantrone )

Catalog No. M18958 CAS No. 65271-80-9

Mitoxantrone is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	48	In Stock
25MG	31	In Stock
50MG	44	In Stock
100MG	60	In Stock
200MG	101	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Mitoxantrone
Note

Research use only, not for human use.
Brief Description

Mitoxantrone is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication.
Description

Mitoxantrone is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin.
In Vitro

——
In Vivo

——
Synonyms

mitozantrone
Pathway

Others
Target

Other Targets
Recptor

Topo II
Research Area

Cancer
Indication

——

Chemical Information

CAS Number

65271-80-9
Formula Weight

444.48
Molecular Formula

C22H28N4O6
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 150 mg/mL; 337.47 mM
SMILES

OCCNCCNc1ccc(NCCNCCO)c2c1C(=O)c1c(O)ccc(O)c1C2=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Bellosillo B, et al. Br J Haematol, 1998, 100(1), 142-146.

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