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Mitoxantrone
CAS No. 65271-80-9
Mitoxantrone( mitozantrone )
Catalog No. M18958 CAS No. 65271-80-9
Mitoxantrone is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
|
| 25MG | 31 | In Stock |
|
| 50MG | 44 | In Stock |
|
| 100MG | 60 | In Stock |
|
| 200MG | 101 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMitoxantrone
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NoteResearch use only, not for human use.
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Brief DescriptionMitoxantrone is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication.
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DescriptionMitoxantrone is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin.
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In Vitro——
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In Vivo——
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Synonymsmitozantrone
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PathwayOthers
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TargetOther Targets
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RecptorTopo II
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number65271-80-9
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Formula Weight444.48
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Molecular FormulaC22H28N4O6
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 150 mg/mL; 337.47 mM
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SMILESOCCNCCNc1ccc(NCCNCCO)c2c1C(=O)c1c(O)ccc(O)c1C2=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bellosillo B, et al. Br J Haematol, 1998, 100(1), 142-146.
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