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4-Hydroxyquinoline

CAS No. 611-36-9

4-Hydroxyquinoline( 4-Hydroxyquinoline | 4 Hydroxyquinoline | Kynurine | )

Catalog No. M18890 CAS No. 611-36-9

4-Hydroxyquinoline is a hydroxylated quinoline derivative with antimicrobial activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    4-Hydroxyquinoline
  • Note
    Research use only, not for human use.
  • Brief Description
    4-Hydroxyquinoline is a hydroxylated quinoline derivative with antimicrobial activity.
  • Description
    4-Hydroxyquinoline is a quinolone compound which forms the core moiety of antibacterials.
  • In Vitro
    4-Quinolone (Kynurine) promotes tumor cell survival and motility by suppressing antitumor immune responses through AhR in an autocrine/paracrine fashion. This system is particularly active in human brain tumors where the activation of AhR enhances the expression of TDO producing more kynurine and kynurinic acid. In the healthy human brain, very low levels of TDO exist, whereas, in human brain tumors, the TDO protein levels increase with malignancy.
  • In Vivo
    ——
  • Synonyms
    4-Hydroxyquinoline | 4 Hydroxyquinoline | Kynurine |
  • Pathway
    Others
  • Target
    Antioxidant
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    611-36-9
  • Formula Weight
    145.16
  • Molecular Formula
    C9H7NO
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (688.90 mM)
  • SMILES
    Oc1ccnc2ccccc12
  • Chemical Name
    4-Hydroxyquinoline

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Criado S, et al. Journal of Photochemistry & Photobiology B Biology, 2003, 71(1):19-25.
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