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Engeletin
CAS No. 572-31-6
Engeletin( —— )
Catalog No. M18834 CAS No. 572-31-6
Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 43 | In Stock |
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| 5MG | 39 | In Stock |
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| 10MG | 64 | In Stock |
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| 25MG | 141 | In Stock |
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| 50MG | 221 | In Stock |
|
| 100MG | 393 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameEngeletin
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NoteResearch use only, not for human use.
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Brief DescriptionEngeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml.
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DescriptionEngeletin may serve as a potential anti-inflammatory agent. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engeletin inhibits a recombinant human aldose reductase (IC5 value=1.16 microM).
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In VitroEngeletin is a flavanonol glycoside isolated from hymenaea martiana, inhibits NF-κB signaling-pathway activation.
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In VivoEngeletin (25, 50, 100 mg/kg, i.p.) markedly reduces LPS-increased myeloperoxidase activity in mice, activates NF-κB-pathway activation, decreases the production of inflammatory mediators (iNOS and COX-2), and suppresses the expression of TLR4-signaling downstream molecules such as MyD88, IRAK1, TRAF6, and TAK1 proteins.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorAldose reductase
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number572-31-6
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Formula Weight434.39
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Molecular FormulaC21H22O10
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 83.3 mg/mL; 191.76 mM
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SMILESCC1C(C(C(C(O1)OC2C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC=C(C=C4)O)O)O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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