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Aloperine
CAS No. 56293-29-9
Aloperine( Aloperine )
Catalog No. M18812 CAS No. 56293-29-9
Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 29 | In Stock |
|
| 100MG | 34 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 81 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAloperine
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NoteResearch use only, not for human use.
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Brief DescriptionAloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.
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DescriptionAloperine is an alkaloid with diverse biological activities including antiviral, anticancer, antioxidant, and anti-inflammatory actions. It inhibits HIV-1 replication and envelope-mediated cell-cell fusion in vitro. Aloperine also inhibits the growth of HL-60, U937, and K562 leukemia cell lines.
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In VitroAloperine (1-20 μM; 24 hours) gives growth-inhibitory IC50 values in cancer cells ranges from 0.04 to 1.36 mM, the IC50 values in HL-60, U937, K562, EC109, A549 and HepG2 cells are 0.04, 0.27, 0.36, 1.11, 1.18 and 1.36 mM,respectively.Aloperine (1-20 μM; 24 hours) induces apoptosis and decreases bcl-2 expression in HL-60 cells.Aloperine (20–100 μM; 18 hours) induces autophagy and formation of acidic vacuole in HL-60 cells.
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In Vivo——
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SynonymsAloperine
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number56293-29-9
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Formula Weight232.36
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Molecular FormulaC15H24N2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 5.56 mg/mL (23.93 mM)
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SMILESC1CCN2C[C@H]3C[C@@H]([C@H]2C1)C=C1[C@H]3NCCC1
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Chemical Name(6R,6aR,13R,13aS)-1,3,4,6,6a,7,8,9,10,12,13,13a-dodecahydro-2H-6,13-methanodipyrido[1,2-a:3',2'-e]azocine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Yuan XY, et al. Eur J Pharmacol, 2010, 629(1-3), 147-152.
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