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n-Butylidenephthalide
CAS No. 551-08-6
n-Butylidenephthalide( Butylidenephthalide | BP | 3-Butylidene Phthalide )
Catalog No. M18790 CAS No. 551-08-6
(Z)-3-butylidenephthalide has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(5) 2.35 mM) in a noncompetitive fashion with a K(i) of 4.86 mM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 35 | In Stock |
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| 5MG | 29 | In Stock |
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| 10MG | 46 | In Stock |
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| 25MG | 72 | In Stock |
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| 50MG | 100 | In Stock |
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| 100MG | 145 | In Stock |
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| 200MG | 212 | In Stock |
|
| 500MG | 362 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Namen-Butylidenephthalide
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NoteResearch use only, not for human use.
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Brief Description(Z)-3-butylidenephthalide has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(5) 2.35 mM) in a noncompetitive fashion with a K(i) of 4.86 mM.
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DescriptionButylidenephthalide is an inhibitor of platelet-derived growth factor (PDGF). Butylidenephthalide activity leads to the reduction of liver fibrosis, increased Nur77 (NR4A1) expression, and downregulation of EMT-related genes such as Snail (Snail/SNAI1) and Slug (Slug/SNAI2).
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In Vitro3-Butylidenephthalide (Butylidenephthalide) abrogates the myofibroblasts activation and mesenchymal transdifferentiation in oral submucous fibrosis.
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In Vivo——
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SynonymsButylidenephthalide | BP | 3-Butylidene Phthalide
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PathwayMembrane Transporter/Ion Channel
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TargetTRP/TRPV Channel
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Recptorα-glucosidase
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Research Area——
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Indication——
Chemical Information
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CAS Number551-08-6
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Formula Weight188.22
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Molecular FormulaC12H12O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (1328.23 mM)
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SMILESCCCC=C1C2=CC=CC=C2C(=O)O1
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Chemical Name3-Butylidene-2-benzofuran-1-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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