Corydaline
CAS No. 518-69-4
Corydaline( Corydalin | BRN 0096972 | NSC-406036 | NSC406036 )
Catalog No. M18708 CAS No. 518-69-4
Corydaline, an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 58 | In Stock |
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| 5MG | 52 | In Stock |
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| 10MG | 85 | In Stock |
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| 25MG | 141 | In Stock |
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| 50MG | 204 | In Stock |
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| 100MG | 303 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameCorydaline
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NoteResearch use only, not for human use.
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Brief DescriptionCorydaline, an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent.
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DescriptionCorydaline is isolated from Corydalis yanhusuo. It exhibits many activities, including increaseing gastric emptying and small intestine transit seed, decreasing chemically induced pain, and potentially suppressing mast cell dependent smooth muscle contracting of the aorta.
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In VitroWestern Blot Analysis Cell Line:Vero cellsinfected with EV71 Concentration:12.5 μM, 25 μM, 50 μM Incubation Time:24 hours Result:Reduced the phosphorylation of P38 MAPK and JNK MAPK and the expression of COX-2.
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In VivoAnimal Model:Male CD1 mice (30-35 g, 7-8 weeks old) injected with acetic acid Dosage:10 mg/kg Administration:Subcutaneous administration; once Result:Showed antinociceptive effects in mice.
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SynonymsCorydalin | BRN 0096972 | NSC-406036 | NSC406036
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PathwayOthers
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TargetOther Targets
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RecptorCYP2C|CYP2C9
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number518-69-4
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Formula Weight369.46
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Molecular FormulaC22H27NO4
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Purity>98% (HPLC)
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SolubilityDMSO : 33.33 mg/mL 90.22 mM; H2O : < 0.1 mg/mL
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SMILESCC1C2C3=CC(=C(C=C3CCN2CC4=C1C=CC(=C4OC)OC)OC)OC
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Chemical NameVRSRXLJTYQVOHC-YEJXKQKISA-N
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Lastourvilline
Lastourvilline
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(Pyr5,N-Me-Phe8,Sar9...
[Glp5,(Me)Phe8,Sar9] Substance P (5-11) (DiMe-C7) is a Substance P analogue that has approximately the same effects as Substance P on neurokinin 1 receptor (NK1R) in rat brain, but with a much longer duration of action. [Glp5,(Me)Phe8,Sar9] Substance P (5-11) selectively activates dopamine metabolism in the mesencephalon and midbrain cortex of the rat brain. [Glp5,(Me)Phe8,Sar9] Substance P (5-11) also increases motor activity and induces recovery of addictive agent-seeking behavior in rats.
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