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Chikusetsusaponin IVa

CAS No. 51415-02-2

Chikusetsusaponin IVa( Calenduloside F )

Catalog No. M18699 CAS No. 51415-02-2

Chikusetsusaponin IVa is a novel AMPK activator, can induce insulin secretion from βTC3 cells via GPR4 mediated calcium and PKC pathways.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 107 In Stock
5MG 84 In Stock
10MG 124 In Stock
25MG 209 In Stock
50MG 303 In Stock
100MG 431 In Stock
200MG 606 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Chikusetsusaponin IVa
  • Note
    Research use only, not for human use.
  • Brief Description
    Chikusetsusaponin IVa is a novel AMPK activator, can induce insulin secretion from βTC3 cells via GPR4 mediated calcium and PKC pathways.
  • Description
    Chikusetsusaponin IVa is a novel AMPK activator, can induce insulin secretion from βTC3 cells via GPR4 mediated calcium and PKC pathways, may be developed into a new potential for therapeutic agent used in T2DM patients.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Calenduloside F
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    AMPK
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    51415-02-2
  • Formula Weight
    794.98
  • Molecular Formula
    C42H66O14
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 100 mg/mL 125.79 mM;
  • SMILES
    C[C@]12CC[C@@H](C([C@@H]1CC[C@@]1([C@@H]2CC=C2[C@]1(CC[C@@]1([C@H]2CC(CC1)(C)C)C(=O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)C)C)(C)C)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)C(=O)O)O)O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Li Y, ET AL. Chikusetsu saponin IVa regulates glucose uptake and fatty acid oxidation: implications in antihyperglycemic and hypolipidemic effects. J Pharm Pharmacol. 2015 Jul;67(7):997-1007.
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