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Epicatechin
CAS No. 490-46-0
Epicatechin( Epicatechin | (-)-Epicatechin | epi-Catechol | NSC 81161 )
Catalog No. M18641 CAS No. 490-46-0
(-)-Epicatechin is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 48 | In Stock |
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| 25MG | 60 | In Stock |
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| 50MG | 77 | In Stock |
|
| 100MG | 108 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameEpicatechin
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NoteResearch use only, not for human use.
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Brief Description(-)-Epicatechin is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB.
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DescriptionEpicatechin is a flavan-3-ol, a type of natural phenol and antioxidant. It is a plant secondary metabolite. The name of the catechin chemical family derives from catechu, which is the tannic juice or boiled extract of Mimosa catechu (Acacia catechu L.f). l-Epicatechin can be found in cacao beans and was first called kakaool or cacao-ol. Maximilian Nierenstein was among those who proved the presence of catechin in cocoa beans in 1931.
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In Vitro——
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In Vivo——
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SynonymsEpicatechin | (-)-Epicatechin | epi-Catechol | NSC 81161
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PathwayMAPK/ERK Signaling
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Targetp38 MAPK
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RecptorOthers
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number490-46-0
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Formula Weight290.28
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Molecular FormulaC15H14O6
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 34 mg/mL; 117.13 mM
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SMILESC1[C@H]([C@H](Oc2cc(cc(c12)O)O)c1cc(c(cc1)O)O)O
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Chemical Name(2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kiewning D, et al. Food Chem. 2013 Sep 1;140(1-2):99-104.
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