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Isofraxidin
CAS No. 486-21-5
Isofraxidin( Isofraxidin | Phytodolor )
Catalog No. M18627 CAS No. 486-21-5
Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 30 | In Stock |
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| 10MG | 36 | In Stock |
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| 25MG | 67 | In Stock |
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| 50MG | 99 | In Stock |
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| 100MG | 146 | In Stock |
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| 200MG | 217 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameIsofraxidin
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NoteResearch use only, not for human use.
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Brief DescriptionIsofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner.
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DescriptionIsofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. Isofraxidin has a protective effect against LPS-induced ALI, and the protective effect of Isofraxidin seems to result from the inhibition of COX-2 protein expression in the lung, which regulates the production of PGE2. Isofraxidin possesses significant analgesic and anti-inflammatory activities that may be mediated through the regulation of pro-inflammatory cytokines, TNF-α and the phosphorylation of p38 and ERK1/2.
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In Vitro——
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In Vivo——
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SynonymsIsofraxidin | Phytodolor
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PathwayOthers
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TargetOther Targets
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Recptorp38|ERK
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number486-21-5
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Formula Weight222.19
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Molecular FormulaC11H10O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (1125.16 mM)
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SMILESCOC1=C(C(=C2C(=C1)C=CC(=O)O2)OC)O
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Chemical Name7-Hydroxy-6,8-dimethoxychromen-2-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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8-Hydroxygenistein
8-Hydroxygenistein (8-OHG) is an antioxidant that can effectively scavenge nitric oxide (NO) and superoxide anion (O??). 8-Hydroxygenistein belongs to ortho-dihydroxy isoflavones (ODI) and is abundantly present in dark soy sauce and light soy sauce. Its antioxidant activity is stronger than that of its parent compound genistein. The content of 8-Hydroxygenistein is positively correlated with the antioxidant capacity of soy sauce (r = 0.959), and it remains highly stable even after being heated in boiling water for 60 minutes. During the brewing and storage of soy sauce, 8-Hydroxygenistein effectively prevents oxidative damage, making it promising for use in food antioxidant research.
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8-Hydroxypinoresinol...
The barks of Eucommia ulmoides.
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AB-680
AB-680 is a highly potent, reversible, and selective inhibitor of CD73 (an ectonucleotidase, Ki: 4.9 pM for hCD73) with anti-tumor activity.
