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Isosakuranetin
CAS No. 480-43-3
Isosakuranetin( —— )
Catalog No. M18612 CAS No. 480-43-3
Isosakuranetin has cytotoxic and fungicide properties. Isosakuranetin produces significant decrease in blood pressure.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 139 | In Stock |
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| 5MG | 92 | In Stock |
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| 10MG | 132 | In Stock |
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| 25MG | 221 | In Stock |
|
| 50MG | 321 | In Stock |
|
| 100MG | 476 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameIsosakuranetin
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NoteResearch use only, not for human use.
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Brief DescriptionIsosakuranetin has cytotoxic and fungicide properties. Isosakuranetin produces significant decrease in blood pressure.
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DescriptionIsosakuranetin has cytotoxic and fungicide properties. Isosakuranetin produces significant decrease in blood pressure. Isosakuranetin significantly reduces the sensitivity of mice to noxious heat and PregS-induced chemical pain.
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In VitroIsosakuranetin stimulates melanin accumulation in a dose-dependent manner. In addition, Isosakuranetin at 30 μM gradually increases the expression of Tyr, TRP1, and TRP2 after 48 and 72 h. The MTT assay shows that Isosakuranetin decreases the number of cells at concentrations greater than 45 μM. Further analysis of trypan blue staining demonstrates that Isosakuranetin does not affect the viability of B16 melanocytes, but shows that Isosakuranetin decreases their proliferation rate. The tyrosinase activity of B16 melanocytes treated with 15 and 30 μM Isosakuranetin for 72 h is significantly increased by 2- and 3.2-fold, respectively, in comparison with that of the control cells.
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In VivoIsosakuranetin dose-dependently increases the paw-withdrawal threshold within the dose range of 1.5 to 6 mg/kg. Post hoc analysis reveals that Isosakuranetin increases the paw-withdrawal threshold and statistical significance is seen at times 30 and 40 min for the dose of 3 mg/kg and 30 to 60 min for the dose of 6 mg/kg.
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Synonyms——
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PathwayOthers
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TargetAntioxidant
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RecptorOthers
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number480-43-3
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Formula Weight286.28
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Molecular FormulaC16H14O5
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Purity>98% (HPLC)
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SolubilityDMSO : 125 mg/mL 436.64 mM;
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SMILESCOC1=CC=C(C=C1)C2CC(=O)C3=C(C=C(C=C3O2)O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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