Prasugrel Hydrochloride( Prasugrel Hydrochloride )

Catalog No. M18511 CAS No. 389574-19-0

Prasugrel hydrochloride is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	48	In Stock
50MG	34	In Stock
100MG	48	In Stock
200MG	Get Quote	In Stock
500MG	120	In Stock
1G	179	In Stock

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Biological Information

Product Name

Prasugrel Hydrochloride
Note

Research use only, not for human use.
Brief Description

Prasugrel hydrochloride is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.
Description

Prasugrel Hydrochloride is A piperazine derivative and platelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome; unstable angina and myocardial infarction, as well as in those undergoing percutaneous coronary interventions.(In Vivo):In rat platelets, Prasugrel hydrochloride active metabolite inhibits in vitro platelet aggregation induced by adenosine ADP (10μM) with an IC50 value of 1.8 μM.Prasugrel hydrochloride acts faster and is significantly more potent than Clopidogrel in vivo. Prasugrel hydrochloride is an inactive prodrug that requires metabolic processing in vivo to generate the active antiplatelet metabolite. Prasugrel hydrochloride is rapidly absorbed from the gut. After oral administration of standard-loading doses of 60 mg, maximum plasma levels of the active metabolite are achieved within 1 h, effective, maximum inhibition of platelet aggregation at 1-2 h.
In Vitro

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In Vivo

In rat platelets, Prasugrel hydrochloride active metabolite inhibits in vitro platelet aggregation induced by adenosine ADP (10μM) with an IC50 value of 1.8 μM.Prasugrel hydrochloride acts faster and is significantly more potent than Clopidogrel in vivo. Prasugrel hydrochloride is an inactive prodrug that requires metabolic processing in vivo to generate the active antiplatelet metabolite. Prasugrel hydrochloride is rapidly absorbed from the gut. After oral administration of standard-loading doses of 60 mg, maximum plasma levels of the active metabolite are achieved within 1 h, effective, maximum inhibition of platelet aggregation at 1-2 h.
Synonyms

Prasugrel Hydrochloride
Pathway

Others
Target

Other Targets
Recptor

P2Y12
Research Area

Cardiovascular Disease
Indication

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Chemical Information

CAS Number

389574-19-0
Formula Weight

409.9
Molecular Formula

C20H20FNO3S·HCl
Purity

>98% (HPLC)
Solubility

DMSO : 41.67 mg/mL 101.66 mM
SMILES

Cl.CC(=O)OC1=CC2=C(CCN(C2)C(C(=O)C2CC2)C2=C(F)C=CC=C2)S1
Chemical Name

Ethanone, 2-(2-(acetyloxy)-6,7-dihydrothieno(3,2-c)pyridin-5(4H)-yl)-1-cyclopropyl-2-(2-fluorophenyl)-, hydrochloride