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4-Octyl itaconate
CAS No. 3133-16-2
4-Octyl itaconate( 4-Octyl Itaconate | 4 Octyl Itaconate | 4-Octyl-Itaconate )
Catalog No. M18412 CAS No. 3133-16-2
4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 42 | In Stock |
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| 25MG | 29 | In Stock |
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| 50MG | 37 | In Stock |
|
| 100MG | 54 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name4-Octyl itaconate
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NoteResearch use only, not for human use.
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Brief Description4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
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Description4-Octyl Itaconate is a cell permeable activator of Nrf2 which inhibits LPS-induced increases in IL-1β mRNA, HIF-1α, and IL-10 in macrophages.
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In Vitro——
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In Vivo——
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Synonyms4-Octyl Itaconate | 4 Octyl Itaconate | 4-Octyl-Itaconate
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PathwayOthers
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TargetOther Targets
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RecptorKeap1-Nrf2
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Research Area——
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Indication——
Chemical Information
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CAS Number3133-16-2
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Formula Weight242.31
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Molecular FormulaC13H22O4
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 150 mg/mL; 619.04 mM
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SMILESCCCCCCCCOC(=O)CC(=C)C(O)=O
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Chemical Name2-Methylene-4-(octyloxy)-4-oxobutanoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Mills EL, et al. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature. 2018 Apr 5;556(7699):113-117.
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