Dihydromyricetin( Ampelopsin | Ampeloptin )

Catalog No. M18341 CAS No. 27200-12-0

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Dihydromyricetin
Note

Research use only, not for human use.
Brief Description

Dihydromyricetin is a potent inhibitor of dihydropyrimidinase with an IC50 of 48 μM. Dihydromyricetin can activate autophagy by inhibiting mTOR signaling.
Description

Ampelopsin, also known as dihydromyricetin, is a type of flavonoid. It can be found in Cedrus deodara or in the Japanese raisin tree (Hovenia dulcis). It is also found in Erythrophleum africanum. The compound is credited with hepatoprotective effects observed in rodents. Use of Hovenia species in traditional Chinese herbal medicine as a hangover cure has led to research into the potential action of dihydromyricetin in counteracting the effects of alcohol in the brain.
In Vitro

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In Vivo

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Synonyms

Ampelopsin | Ampeloptin
Pathway

Others
Target

Other Targets
Recptor

GABAR
Research Area

Cancer
Indication

——

CAS Number

27200-12-0
Formula Weight

320.25
Molecular Formula

C15H12O8
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 100 mg/mL; 312.26 mM
SMILES

C1=C(C=C(C(=C1O)O)O)[C@@H]2[C@H](C(=O)C3=C(C=C(C=C3O2)O)O)O
Chemical Name

(2R,3R)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one

1. Zhang YS, et al. Yao Xue Xue Bao, 2003, 38(4), 241-244.

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