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Bisdemethoxycurcumin
CAS No. 24939-16-0
Bisdemethoxycurcumin( Curcumin III, Bisdemethoxycurcumin )
Catalog No. M18307 CAS No. 24939-16-0
Bisdemethoxycurcumin (BDMC) is a natural demethoxy derivative of curcumin.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 33 | In Stock |
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| 5MG | 29 | In Stock |
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| 10MG | 46 | In Stock |
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| 25MG | 72 | In Stock |
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| 50MG | 100 | In Stock |
|
| 100MG | 151 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 369 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBisdemethoxycurcumin
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NoteResearch use only, not for human use.
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Brief DescriptionBisdemethoxycurcumin (BDMC) is a natural demethoxy derivative of curcumin.
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DescriptionBisdemethoxycurcumin (BDMC) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis, interacting with 1α, 25-dihydroxy vitamin D3 to stimulate amyloid-β clearance by macrophages (optimal stimulation at 100 nM BDMC) [1]. More stable than curcumin in physiological media, BDMC suppresses proliferation of cancer cells. It down-regulates the transcriptional coactivator p300, suppressing the Wnt/β-catenin pathway, and inhibits LPS induction of iNOS expression.
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In Vitro——
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In Vivo——
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SynonymsCurcumin III, Bisdemethoxycurcumin
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PathwayOthers
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TargetOther Targets
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Recptorp300|Wnt/β-catenin
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number24939-16-0
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Formula Weight308.33
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Molecular FormulaC19H16O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 66.67 mg/mL (216.23 mM)
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SMILESOc2ccc(/C=C/C(=O)CC(=O)/C=C/c1ccc(O)cc1)cc2
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Chemical Name(1E,6E)-1,7-Bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Fiala, M., Liu, P.T., Espinosa-Jeffrey, A., et al. Proceedings of the National Academy of Sciences of the United States of America 104(31), 12849-12854 (2007).
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