Cart
sales@molnova.com
Senegenin
CAS No. 2469-34-3
Senegenin( —— )
Catalog No. M18304 CAS No. 2469-34-3
Senegenin is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 57 | In Stock |
|
| 2MG | 29 | In Stock |
|
| 5MG | 46 | In Stock |
|
| 10MG | 67 | In Stock |
|
| 25MG | 107 | In Stock |
|
| 50MG | 152 | In Stock |
|
| 100MG | 222 | In Stock |
|
| 200MG | 328 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSenegenin
-
NoteResearch use only, not for human use.
-
Brief DescriptionSenegenin is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.
-
DescriptionSenegenin is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.
-
In Vitro——
-
In VivoTenuigenin (2, 4, 8 mg/kg) significantly attenuates S.aureus-induced lung histopathological changes. Tenuigenin also inhibits lung wet/dry (W/D) ratio, and inflammatory cytokines TNF-α and IL-1β production in Male BALB/c mice.
-
Synonyms——
-
PathwayMAPK/ERK Signaling
-
Targetp38 MAPK
-
RecptorCaspase-3
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2469-34-3
-
Formula Weight537.1
-
Molecular FormulaC30H45ClO6
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (186.17 mM)
-
SMILESC1[C@@H]([C@@H]([C@]([C@@H]2CC[C@]3(C4=C([C@H]5[C@@](CC4)(CCC(C5)(C)C)C(=O)O)[C@H](C[C@@H]3[C@@]12C)CCl)C)(C(=O)O)C)O)O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Li X, Zhao Y, Liu P,et al.Senegenin Inhibits Hypoxia/Reoxygenation-Induced Neuronal Apoptosis by Upregulating RhoGDIα.Mol Neurobiol. 2015 Dec;52(3):1561-71.
molnova catalog
related products
-
Asiatic acid
ActionsAsiatic acid is commonly used in wound healing. Asiatic acid has antioxidant,anti-inflammatory and neuroprotective properties.
-
AKP-001
AKP-001 is a selective inhibitor of MAPK of the p38α isoform and is used in the study of immune and digestive disorders.
-
SR-318
SR-318 potently inhibits the TNF-α release in whole blood (IC50 = 283 nM). SR-318 is a potent and highly selective inhibitor of p38 MAPK. The IC50 values are 5 nM, 32 nM and 6.11 μM for p38α, p38β and p38α/β, respectively.
