PTP1B-IN-2( PTP1B-IN-2 | PTP1B-IN-2 | MDK3465 )

Catalog No. M18177 CAS No. 1919853-46-5

PTP1B-IN-2 is an effective protein tyrosine phosphatase 1B (PTP1B) inhibitor(IC50=50 nM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	140	In Stock
5MG	93	In Stock
10MG	132	In Stock
25MG	264	In Stock
50MG	384	In Stock
100MG	554	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

PTP1B-IN-2
Note

Research use only, not for human use.
Brief Description

PTP1B-IN-2 is an effective protein tyrosine phosphatase 1B (PTP1B) inhibitor(IC50=50 nM).
Description

MDK3465, also known as PTP1B-IN-2, is a potent and selective protein tyrosine phosphatase-1B (PTP1B) inhibitor. MDK3465 has CAS#1919853-46-5. The last 4 digit of its CAS# is used for name.
In Vitro

——
In Vivo

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Synonyms

PTP1B-IN-2 | PTP1B-IN-2 | MDK3465
Pathway

Cytoskeleton/Cell Adhesion Molecules
Target

Akt
Recptor

PTP1B
Research Area

——
Indication

——

Chemical Information

CAS Number

1919853-46-5
Formula Weight

680.79
Molecular Formula

C34H36N2O9S2
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 100 mg/mL; 146.89 mM
SMILES

CC1=CC=C(C=C1)COC2=C(C=C(C=C2)N(CC3=CC=C(C=C3)N(CC(=O)OC)S(=O)(=O)C)S(=O)(=O)CC4=CC=CC=C4)C(=O)OC
Chemical Name

methyl 5-((4-((N-(4-(N-(2-methoxy-2-oxoethyl)methylsulfonamido)benzyl)-1-phenylmethyl)sulfonamido)phenoxy)methyl)-2-methylbenzoate

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Liu P, et al. Discovery of novel, high potent, ABC type PTP1B inhibitors with TCPTP selectivity and cellular activity. Eur J Med Chem. 2016 Aug 8;118:27-33.

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