LTI-291
CAS No. 1919820-28-2
LTI-291( LTI-291 | LTI 291 | LTI291 )
Catalog No. M18176 CAS No. 1919820-28-2
LTI-291 is a glucocerebrosidase (Gcase) activator.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 102 | In Stock |
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| 2MG | 55 | In Stock |
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| 5MG | 92 | In Stock |
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| 10MG | 148 | In Stock |
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| 25MG | 297 | In Stock |
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| 50MG | 461 | In Stock |
|
| 100MG | 709 | In Stock |
|
| 200MG | 918 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameLTI-291
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NoteResearch use only, not for human use.
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Brief DescriptionLTI-291 is a glucocerebrosidase (Gcase) activator.
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DescriptionLTI-291 is a glucocerebrosidase (Gcase) activator for treatment of Parkinson's disease (PD).
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In Vitro——
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In Vivo——
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SynonymsLTI-291 | LTI 291 | LTI291
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PathwayOthers
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TargetOther Targets
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Recptorβ-glucosidase
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number1919820-28-2
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Formula Weight358.49
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Molecular FormulaC20H30N4O2
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Purity>98% (HPLC)
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SolubilityDMSO : 50 mg/mL 139.48 mM;
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SMILESO=C(C1=C2N=C(C)C=C(C)N2N=C1)N[C@H]3CC[C@H](OCCCCC)CC3
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Chemical Name5,7-Dimethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (trans-4-pentyloxy-cyclohexyl)-amide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Renato T. Skerlj, et al. Methods of treatment and combination therapies using gcase activator heterobicyclic and related compounds. WO 2017192841 A1.
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Dehydrodicatechin A
The peroxidase-mediated (+)-catechin oxidation was differentially inhibited by dehydrodicatechin A, showing a competitive type inhibition and a k(I) of 6.4 microM.
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