TAPI-1

CAS No. 171235-71-5

TAPI-1( TAPI-1 | TNF-alpha Protease Inhibitor-1 )

Catalog No. M18119 CAS No. 171235-71-5

TAPI-1, an ADAM17/TACE inhibitor, inhibits shedding of cytokine receptors.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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50MG 2232 In Stock
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Biological Information

  • Product Name
    TAPI-1
  • Note
    Research use only, not for human use.
  • Brief Description
    TAPI-1, an ADAM17/TACE inhibitor, inhibits shedding of cytokine receptors.
  • Description
    TAPI-1 is and inhibitor of TACE. It inhibits the cleavage of TNF-a, TNFRI (p60), and TNFRII (p80).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    TAPI-1 | TNF-alpha Protease Inhibitor-1
  • Pathway
    GPCR/G Protein
  • Target
    GHSR
  • Recptor
    ADAM17/TACE
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    171235-71-5
  • Formula Weight
    499.6
  • Molecular Formula
    C26H37N5O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)CC(CC(=O)NO)C(=O)N[C@@H](Cc1cc2ccccc2cc1)C(=O)N[C@@H](C)C(=O)NCCN
  • Chemical Name
    N-[(2S)-1-[[(2S)-1-(2-Aminoethylamino)-1-oxopropan-2-yl]amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Müllberg J, et al. J Immunol. 1995, 155(11), 5198-5205.
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