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Picolinamide
CAS No. 1452-77-3
Picolinamide( —— )
Catalog No. M18028 CAS No. 1452-77-3
Picolinamide is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | 27 | In Stock |
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Biological Information
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Product NamePicolinamide
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NoteResearch use only, not for human use.
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Brief DescriptionPicolinamide is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.
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DescriptionPicolinamide is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.
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In VitroPicolinamide (10 μM-1 mM) inhibits Poly(ADP-ribose) synthetase activity.Picolinamide (2 mM) protects against streptozotocin-induced depression of proinsulin synthesis in isolated pancreatic islets of rats.
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In VivoPicolinamide (4 mmol/kg, i.p., rats) inhibits Na+/phosphate cotransport by isolated renal brush border membrane vesicles.Picolinamide (250 mg/kg, i.p., rats) enhances the tumorigenic effect of Streptozotocin and Alloxan on islet B-cells. Animal Model:Rats Dosage:4 mmol/kg Administration:Intraperitoneal injection (i.p.)Result:Increased renal cortical NAD content (1.5 fold).
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorPARP
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1452-77-3
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Formula Weight122.12
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Molecular FormulaC6H6N2O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 100 mg/mL (818.87 mM)
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SMILESC1=CC=NC(=C1)C(=O)N
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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