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Didymin
CAS No. 14259-47-3
Didymin( —— )
Catalog No. M18013 CAS No. 14259-47-3
Didymin has antioxidant property. Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma, may used for neuroblastoma therapy.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 64 | In Stock |
|
| 10MG | 111 | In Stock |
|
| 25MG | 183 | In Stock |
|
| 50MG | 263 | In Stock |
|
| 100MG | 390 | In Stock |
|
| 200MG | 581 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDidymin
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NoteResearch use only, not for human use.
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Brief DescriptionDidymin has antioxidant property. Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma, may used for neuroblastoma therapy.
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DescriptionDidymin has antioxidant property. Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma, may used for neuroblastoma therapy. Didymin may be a potential therapeutic molecule for the treatment of neurodegenerative disorders associated with oxidative stress.
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In VitroCell Proliferation Assay Cell Line:A549 and H460 cells Concentration:1 μM, 5 μM, 10 μM, 20 μM Incubation Time:48 h Result:Inhibited cell proliferation in human non-small-cell lung cancer cells.Apoptosis Analysis Cell Line:A549 and H460 cells Concentration:10 μM, 20 μM Incubation Time:12 h, 24 h, 48 h Result:Induced apoptosis in A549 and H460 cells, without affecting the cell cycle distribution.
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In VivoAnimal Model:Male nude mice [6 weeks old; BALB/cA-nu (nu/nu)] injected with A549 cells Dosage:6 mg/kg/day Administration:i.p.; daily for 28 days Result:Inhibited tumor growth in nude mice.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number14259-47-3
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Formula Weight594.57
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Molecular FormulaC28H34O14
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (420.48 mM)
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SMILESC[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)Oc1cc(c2C(=O)C[C@H](Oc2c1)c1ccc(cc1)OC)O)O)O)O)O)O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Morelli S, et al. Neuroprotective effect of didymin on hydrogen peroxide-induced injury in the neuronal membrane system. Cells Tissues Organs. 2014;199(2-3):184-200.
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