ML133 HCl
CAS No. 1222781-70-5
ML133 HCl( —— )
Catalog No. M17888 CAS No. 1222781-70-5
ML133 HCl is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 46 | In Stock |
|
| 5MG | 41 | In Stock |
|
| 10MG | 58 | In Stock |
|
| 25MG | 103 | In Stock |
|
| 50MG | 161 | In Stock |
|
| 100MG | 268 | In Stock |
|
| 200MG | 347 | In Stock |
|
| 500MG | 585 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameML133 HCl
-
NoteResearch use only, not for human use.
-
Brief DescriptionML133 HCl is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.
-
DescriptionML133 HCl is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAngiogenesis
-
TargetCDK
-
RecptorKir2.1
-
Research AreaOthers-Field
-
Indication——
Chemical Information
-
CAS Number1222781-70-5
-
Formula Weight313.82
-
Molecular FormulaC19H19NO·HCl
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 125 mg/mL; 398.32 mM
-
SMILESCl.COC1=CC=C(CNCC2=CC=CC3=C2C=CC=C3)C=C1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Wang HR, et al. ACS Chem Biol, 2011, 6(8), 845-856.
molnova catalog
related products
-
SU-9516 (b)
SU9516 is a selectively potent ATP-competitive inhibitor of CDKs.
-
Senexin-A
A selective inhibitor of CDK8 (IC50=0.28 uM) and CDK19; inhibits CDK8 and CDK19 ATP site binding with Kd50 of 0.83 uM and 0.31 uM, respectively.
-
THZ-1 hydrochloride
THZ-1 hydrochloride is a potent, selective, covalent CDK7 inhibitor with IC50 of 3.2 nM; also weakly inhibits CDK12 with IC50 of 250 nM.
Cart
sales@molnova.com