ML133 HCl
CAS No. 1222781-70-5
ML133 HCl( —— )
Catalog No. M17888 CAS No. 1222781-70-5
ML133 HCl is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 46 | In Stock |
|
| 5MG | 41 | In Stock |
|
| 10MG | 58 | In Stock |
|
| 25MG | 103 | In Stock |
|
| 50MG | 161 | In Stock |
|
| 100MG | 268 | In Stock |
|
| 200MG | 347 | In Stock |
|
| 500MG | 585 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameML133 HCl
-
NoteResearch use only, not for human use.
-
Brief DescriptionML133 HCl is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.
-
DescriptionML133 HCl is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAngiogenesis
-
TargetCDK
-
RecptorKir2.1
-
Research AreaOthers-Field
-
Indication——
Chemical Information
-
CAS Number1222781-70-5
-
Formula Weight313.82
-
Molecular FormulaC19H19NO·HCl
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 125 mg/mL; 398.32 mM
-
SMILESCl.COC1=CC=C(CNCC2=CC=CC3=C2C=CC=C3)C=C1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Wang HR, et al. ACS Chem Biol, 2011, 6(8), 845-856.
molnova catalog
related products
-
THZ-1
A potent, selective, covalent CDK7 inhibitor with IC50 of 3.2 nM; also weakly inhibits CDK12 with IC50 of 250 nM; displays broad-based activity a subset of cancer cell lines with IC50s of <200 nM.
-
Bohemine
Bohemine is a cyclin-dependent kinase inhibitor.
-
Olomoucine
A potent, ATP-competetive CDKs inhibitor with IC50 of 7, 7, 7, 3 uM for Cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, and Cdk/p35 kinase; also inhibits ERK1/MAP kinase (IC50=25 uM).
Cart
sales@molnova.com