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Demethylzeylasteral
CAS No. 107316-88-1
Demethylzeylasteral( Demethylzeylasteral | T-96 | T 96 )
Catalog No. M17795 CAS No. 107316-88-1
Demethylzeylasteral has strong immunosuppressive activity, can be used in the fields of organ transplantation and autoimmune disorders.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
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| 5MG | 43 | In Stock |
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| 10MG | 65 | In Stock |
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| 25MG | 111 | In Stock |
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| 50MG | 141 | In Stock |
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| 100MG | 183 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDemethylzeylasteral
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NoteResearch use only, not for human use.
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Brief DescriptionDemethylzeylasteral has strong immunosuppressive activity, can be used in the fields of organ transplantation and autoimmune disorders.
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DescriptionDemethylzeylasteral has strong immunosuppressive activity, can be used in the fields of organ transplantation and autoimmune disorders. The risk of elevated serum concentrations of estradiol due to the inhibition of estradiol glucuronidation by Demethylzeylasteral. Demethylzeylasteral increases both activation and inactivation time constants of Ca(2+) currents, can inhibit significantly the sperm acrosome reaction initiated by progesterone.
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In Vitro——
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In Vivo——
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SynonymsDemethylzeylasteral | T-96 | T 96
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PathwayOthers
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TargetOther Targets
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RecptorUGT1A6| UGT2B7
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number107316-88-1
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Formula Weight480.59
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Molecular FormulaC29H36O6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (520.19 mM)
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SMILESC[C@]12CC[C@@](C[C@H]1[C@@]1(CC[C@]3(c4cc(c(c(c4C(=O)C=C3[C@]1(CC2)C)C=O)O)O)C)C)(C)C(=O)O
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Chemical Name(2S,4aS,6aS,12bR,14aR,14bS)-9-formyl-10,11-dihydroxy-2,4a,6a,12b,14a-pentamethyl-8-oxo-1,2,3,4,4a,5,6,6a,8,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Picrinine
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OD1
Potent rat Nav1.7, human Nav1.4 and rat Nav1.6 channel activator (EC50 values are 7, 10 and 47 nM, respectively). Exhibits minimal activation at mammalian Nav1.2, Nav1.3 and Nav1.5 (EC50 values >3 μM). Inhibits fast inactivation on all channels. Increases peak currents at all voltages and stimulates a persistent Na+ current at hNav1.7 channel. Increases hyperpolarization at Nav1.4 and Nav1.6 channels. Induces spontaneous pain in vivo.
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IR820-PTX
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