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NVP-BSK805 2HCl

CAS No. ——

NVP-BSK805 2HCl ( —— )

Catalog No. M17712 CAS No. ——

NVP-BSK805 2HCl(IC50=0.5 nM), a specific and effective ATP-competitive JAK2 inhibitor, is more than 20-fold specificity over JAK1, JAK3 and TYK2.

Purity : >98% (HPLC)

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Biological Information

Product Name

NVP-BSK805 2HCl
Note

Research use only, not for human use.
Brief Description

NVP-BSK805 2HCl(IC50=0.5 nM), a specific and effective ATP-competitive JAK2 inhibitor, is more than 20-fold specificity over JAK1, JAK3 and TYK2.
Description

NVP-BSK805 2HCl(IC50=0.5 nM), a specific and effective ATP-competitive JAK2 inhibitor, is more than 20-fold specificity over JAK1, JAK3 and TYK2.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

HDAC
Recptor

JAK1| JAK2| JAK3| Tyk2
Research Area

——
Indication

——

Chemical Information

CAS Number

——
Formula Weight

563.47
Molecular Formula

C27H28F2N6O·2HCl
Purity

>98% (HPLC)
Solubility

——
SMILES

C1CNCCC1n1cc(cn1)c1nc2c(cccc2nc1)c1cc(c(c(c1)F)CN1CCOCC1)F.Cl.Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Baffert F, et al. Mol Cancer Ther, 2010, 9(7), 1945-1955.

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