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EPZ020411 2HCl
CAS No. ——
EPZ020411 2HCl ( —— )
Catalog No. M17704 CAS No. ——
EPZ020411 is an effective and specific small molecule PRMT6 inhibitor (IC50=10 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 189 | Get Quote |
|
| 10MG | 301 | Get Quote |
|
| 25MG | 627 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameEPZ020411 2HCl
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NoteResearch use only, not for human use.
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Brief DescriptionEPZ020411 is an effective and specific small molecule PRMT6 inhibitor (IC50=10 nM).
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DescriptionEPZ020411 is an effective and specific small molecule PRMT6 inhibitor (IC50=10 nM).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayImmunology/Inflammation
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TargetTLR
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RecptorPRMT6|PRMT1|PRMT8
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight515.51
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Molecular FormulaC25H40Cl2N4O3
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.Cl.CNCCN(C)Cc1cnnc1c2ccc(cc2)O[C@H]4C[C@H](OCCC3CCOCC3)C4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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CPG-52364
CPG-52364 (CPG52364) is an orally available, small molecule TLR7/8/9 antagonist for the treatment of systemic lupus erythematosus and other autoimmune disorders.
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Procyanidin B1
Procyanidin B1, isolated from commonly eaten fruits, binds to the TLR4/MD-2 complex and has anti-inflammatory activity.Procyanidin B1 (100 μg/mL) inhibits LPS-induced TNF-α production, and expression of MD-2, TRAF6, NF-κB mRNA, phosphorylated p38 MAPK and NF-κB protein in THP1 cells.
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ABR-238901
ABR-238901 is an oral, active S100A8/A9 blocker that inhibits the interaction of S100A8/A9 with its receptors RAGE(receptor for advanced glycation end products) and TLR4 (toll-like receptor 4). ABR-238901 has potential as a compound for the treatment of myocardial infarction (MI).
