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TG100713

CAS No. 925705-73-3

TG100713( TG100713 )

Catalog No. M17665 CAS No. 925705-73-3

TG100713 is a pan-PI3K inhibitor against PI3Kγ, PI3Kδ, PI3Kα and PI3Kβ with IC50 of 50 nM, 24 nM, 165 nM and 215 nM, respectively.

Purity : >98% (HPLC)

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Datasheet

HNMR

HPLC

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Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	35	In Stock
5MG	31	In Stock
10MG	50	In Stock
25MG	102	In Stock
50MG	188	In Stock
100MG	275	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

TG100713
Note

Research use only, not for human use.
Brief Description

TG100713 is a pan-PI3K inhibitor against PI3Kγ, PI3Kδ, PI3Kα and PI3Kβ with IC50 of 50 nM, 24 nM, 165 nM and 215 nM, respectively.
Description

TG100713 is an inhibitor of PI3-kinase (IC50 values are 24, 50, 165 and 215 nM for PI3Kδ, γ, α and β isoforms respectively). Inhibits endothelial cell proliferation.
In Vitro

TG100713 (10 μM; 48 or 72 h) strongly inhibits endothelial cell (EC) proliferation.
In Vivo

——
Synonyms

TG100713
Pathway

Cell Cycle/DNA Damage
Target

ROCK
Recptor

PI3Kδ , PI3Kγ , PI3Kα , PI3Kβ
Research Area

Cancer
Indication

——

Chemical Information

CAS Number

925705-73-3
Formula Weight

254.25
Molecular Formula

C12H10N6
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 6.41 mg/mL (25.21 mM)
SMILES

C1=CC(=CC(=C1)O)C2=CN=C3C(=N2)C(=NC(=N3)N)N
Chemical Name

3-(2,4-diaminopteridin-6-yl)phenol

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Doukas J et al. Proc Natl Acad Sci U S A, 2006, 103(52), 19866-19871.

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