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GSK-25

CAS No. 874119-56-9

GSK-25( —— )

Catalog No. M17637 CAS No. 874119-56-9

GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	91	In Stock
2MG	51	In Stock
5MG	80	In Stock
10MG	113	In Stock
25MG	171	In Stock
50MG	266	In Stock
100MG	445	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

GSK-25
Note

Research use only, not for human use.
Brief Description

GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).
Description

GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

RSK1| mTOR (p70S6K)
Research Area

——
Indication

——

Chemical Information

CAS Number

874119-56-9
Formula Weight

513.34
Molecular Formula

C24H16Cl2F2N6O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (97.40 mM)
SMILES

Clc1nccc(c1)C=2NC(C)=C(C(N=2)c3ccc(Cl)cc3F)C(=O)Nc4cc5cnnc5cc4F
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Sehon CA, et al. J Med Chem. 2008 Nov 13;51(21):6631-4.

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