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GSK-25
CAS No. 874119-56-9
GSK-25( —— )
Catalog No. M17637 CAS No. 874119-56-9
GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 91 | In Stock |
|
| 2MG | 51 | In Stock |
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| 5MG | 80 | In Stock |
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| 10MG | 113 | In Stock |
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| 25MG | 171 | In Stock |
|
| 50MG | 266 | In Stock |
|
| 100MG | 445 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGSK-25
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NoteResearch use only, not for human use.
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Brief DescriptionGSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).
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DescriptionGSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorRSK1| mTOR (p70S6K)
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Research Area——
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Indication——
Chemical Information
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CAS Number874119-56-9
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Formula Weight513.34
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Molecular FormulaC24H16Cl2F2N6O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (97.40 mM)
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SMILESClc1nccc(c1)C=2NC(C)=C(C(N=2)c3ccc(Cl)cc3F)C(=O)Nc4cc5cnnc5cc4F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Sehon CA, et al. J Med Chem. 2008 Nov 13;51(21):6631-4.
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