CFMTI( CFMTI )

Catalog No. M17627 CAS No. 864864-17-5

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

CFMTI
Note

Research use only, not for human use.
Brief Description

CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM).
Description

CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM). The selectivity of CFMTI to mGluR1 is higher 2000-fold than mGluR5.
In Vitro

——
In Vivo

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Synonyms

CFMTI
Pathway

Membrane Transporter/Ion Channel
Target

Beta Amyloid
Recptor

mGluR
Research Area

Cancer
Indication

——

CAS Number

864864-17-5
Formula Weight

349.37
Molecular Formula

C19H16FN5O
Purity

>98% (HPLC)
Solubility

DMSO : 6.2 mg/mL. 17.75 mM;
SMILES

c1(c(nccc1)F)n1nnc(c1C)c1ccc2c(c1)CN(C2=O)C1CC1
Chemical Name

2-Cyclopropyl-5-[1-(2-fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-2,3-dihydro-1H-isoindol-1-one

1.Satow A et al. 2009 Jul;330(1):179-90.

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