CFMTI
CAS No. 864864-17-5
CFMTI( CFMTI )
Catalog No. M17627 CAS No. 864864-17-5
CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 136 | In Stock |
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| 2MG | 75 | In Stock |
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| 5MG | 123 | In Stock |
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| 10MG | 180 | In Stock |
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| 25MG | 321 | In Stock |
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| 50MG | 445 | In Stock |
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| 100MG | 621 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCFMTI
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NoteResearch use only, not for human use.
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Brief DescriptionCFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM).
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DescriptionCFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM). The selectivity of CFMTI to mGluR1 is higher 2000-fold than mGluR5.
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In Vitro——
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In Vivo——
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SynonymsCFMTI
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PathwayMembrane Transporter/Ion Channel
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TargetBeta Amyloid
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RecptormGluR
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number864864-17-5
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Formula Weight349.37
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Molecular FormulaC19H16FN5O
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Purity>98% (HPLC)
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SolubilityDMSO : 6.2 mg/mL. 17.75 mM;
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SMILESc1(c(nccc1)F)n1nnc(c1C)c1ccc2c(c1)CN(C2=O)C1CC1
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Chemical Name2-Cyclopropyl-5-[1-(2-fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-2,3-dihydro-1H-isoindol-1-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Amyloid β-Protein 10...
Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-secretase processing site (Lys16-Leu17 bond). It also contains the HHQK domain (residues 13-16) responsible for binding to microglial cells.
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Homotaurine
Because of its similarity in structure to the neurotransmitter gamma-aminobutyric acid (GABA), it has GABAergic effects and may be useful as an anticonvulsant.
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Amyloid beta-peptide...
Amyloid beta-peptide(25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide. Which has shown neurotoxic activities in cultured cells. The amino acid sequence of Aβ(25-35) peptide is NH2-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-COOH, where the first Gly represents the amino acid 25 and the last Met represents the amino acid 35 and it is also investigated in gel state for the first time.
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