Cart
sales@molnova.com
Multi-kinase inhibitor I
CAS No. 778274-97-8
Multi-kinase inhibitor I( MDK74978 | MDK 74978. Multi-kinase inhibitor I )
Catalog No. M17593 CAS No. 778274-97-8
Multi-kinase inhibitor I is a Multi-kinase inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 80 | In Stock |
|
| 2MG | 44 | In Stock |
|
| 5MG | 72 | In Stock |
|
| 10MG | 103 | In Stock |
|
| 25MG | 187 | In Stock |
|
| 50MG | 276 | In Stock |
|
| 100MG | 398 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameMulti-kinase inhibitor I
-
NoteResearch use only, not for human use.
-
Brief DescriptionMulti-kinase inhibitor I is a Multi-kinase inhibitor.
-
DescriptionMDK74978, also known as Multi-kinase inhibitor I, is a Multi-kinase inhibitor. MDK74978 has CAS#778274-97-8. The last 5 digit was used in its name.
-
In VitroMulti-kinase inhibitor 1 (compound 68) is a potent multi-kinase inhibitor. The protein kinases represent a large family of proteins, which play a central role in the regulation of a wide variety of cellular processes and maintaining control over cellular function. These kinases include receptor tyrosine kinases, such as platelet derived growth factor receptor kinase(PDGF-R), the receptor kinase for stem cell factor, c-Kit, and non-receptor tyrosine kinases, such as the fusion kinase Bcr-abl.
-
In Vivo——
-
SynonymsMDK74978 | MDK 74978. Multi-kinase inhibitor I
-
PathwayAngiogenesis
-
TargetHIF/HIF Prolyl-hydroxylase
-
RecptorMulti-kinase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number778274-97-8
-
Formula Weight418.38
-
Molecular FormulaC20H17F3N4O3
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (239.02 mM)
-
SMILESO=C(NCCO)c1ccc(c2ncnc(Nc3ccc(OC(F)(F)F)cc3)c2)cc1
-
Chemical NameN-(2-Hydroxyethyl)-4-[6-[4-(trifluoromethoxy)anilino]pyrimidin-4-yl]benzamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Chang Hsu Y, et al. Oncotarget. 2016 Nov 15
molnova catalog
related products
-
PHD-1-IN-1
PHD-1-IN-1 is a potent inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) enzyme(IC50 = 0.034 μM).
-
MK-8617
A potent, orally active pan-inhibitor of HIF prolyl hydroxylase (HIF-PHD) with IC50 of 1.0,1.0, and 14 nM for HIF-PHD1, 2, and 3, respectively.
-
PT2385
PT2385 (PT-2385) is a potent, selective, and orally active antagonist of HIF2α, binds to HIF2α PAS-B domain (Kd=50 nM) and disrupts HIF2α/ARNT dimer formation.
