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FDI-6

CAS No. 313380-27-7

FDI-6( FDI-6 | FDI 6 | FDI6 | NCGC00099374 )

Catalog No. M17474 CAS No. 313380-27-7

FDI-6 is an effective and selective inhibitor of FOXM1 that blocks DNA binding. FDI-6 binds to the FOXM1 protein and specifically downregulates FOXM1-activated genes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 76 In Stock
5MG 68 In Stock
10MG 117 In Stock
25MG 202 In Stock
50MG 284 In Stock
100MG 421 In Stock
200MG 617 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    FDI-6
  • Note
    Research use only, not for human use.
  • Brief Description
    FDI-6 is an effective and selective inhibitor of FOXM1 that blocks DNA binding. FDI-6 binds to the FOXM1 protein and specifically downregulates FOXM1-activated genes.
  • Description
    FDI-6 is an inhibitor of FOXM1 that block DNA binding. It act by specifically downregulating FOXM1-activated genes with FOXM1 occupancy confirmed by ChIP-PCR.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    FDI-6 | FDI 6 | FDI6 | NCGC00099374
  • Pathway
    Endocrinology/Hormones
  • Target
    Opioid Receptor
  • Recptor
    FOXM1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    313380-27-7
  • Formula Weight
    437.43
  • Molecular Formula
    C19H11F4N3OS2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 50 mg/mL; 114.30 mM
  • SMILES
    C1=CSC(=C1)C2=NC3=C(C(=C2)C(F)(F)F)C(=C(S3)C(=O)NC4=CC=C(C=C4)F)N
  • Chemical Name
    3-Amino-N-(4-fluorophenyl)-6-thiophen-2-yl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Gormally MV., et al. Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition. Nat Commun. 2014 Nov 12;5:5165.
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