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FDI-6
CAS No. 313380-27-7
FDI-6( FDI-6 | FDI 6 | FDI6 | NCGC00099374 )
Catalog No. M17474 CAS No. 313380-27-7
FDI-6 is an effective and selective inhibitor of FOXM1 that blocks DNA binding. FDI-6 binds to the FOXM1 protein and specifically downregulates FOXM1-activated genes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 76 | In Stock |
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| 5MG | 68 | In Stock |
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| 10MG | 117 | In Stock |
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| 25MG | 202 | In Stock |
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| 50MG | 284 | In Stock |
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| 100MG | 421 | In Stock |
|
| 200MG | 617 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameFDI-6
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NoteResearch use only, not for human use.
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Brief DescriptionFDI-6 is an effective and selective inhibitor of FOXM1 that blocks DNA binding. FDI-6 binds to the FOXM1 protein and specifically downregulates FOXM1-activated genes.
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DescriptionFDI-6 is an inhibitor of FOXM1 that block DNA binding. It act by specifically downregulating FOXM1-activated genes with FOXM1 occupancy confirmed by ChIP-PCR.
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In Vitro——
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In Vivo——
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SynonymsFDI-6 | FDI 6 | FDI6 | NCGC00099374
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PathwayEndocrinology/Hormones
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TargetOpioid Receptor
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RecptorFOXM1
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Research Area——
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Indication——
Chemical Information
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CAS Number313380-27-7
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Formula Weight437.43
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Molecular FormulaC19H11F4N3OS2
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 50 mg/mL; 114.30 mM
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SMILESC1=CSC(=C1)C2=NC3=C(C(=C2)C(F)(F)F)C(=C(S3)C(=O)NC4=CC=C(C=C4)F)N
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Chemical Name3-Amino-N-(4-fluorophenyl)-6-thiophen-2-yl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Gormally MV., et al. Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition. Nat Commun. 2014 Nov 12;5:5165.
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