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SB273005

CAS No. 205678-31-5

SB273005( SB-273005 | SB 273005 | SB273005 )

Catalog No. M17422 CAS No. 205678-31-5

SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.

Purity : >98% (HPLC)

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Biological Information

Product Name

SB273005
Note

Research use only, not for human use.
Brief Description

SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.
Description

SB-273005 is an inhibitor of integrin αvβ3.
In Vitro

——
In Vivo

——
Synonyms

SB-273005 | SB 273005 | SB273005
Pathway

Tyrosine Kinase
Target

Src
Recptor

αVβ3 integrin| αVβ5 integrin
Research Area

Inflammation/Immunology
Indication

——

Chemical Information

CAS Number

205678-31-5
Formula Weight

451.44
Molecular Formula

C22H24F3N3O4
Purity

>98% (HPLC)
Solubility

——
SMILES

CNC1=CC=CC(CCOC2=CC=C3C[C@@H](CC(O)=O)C(=O)N(CC(F)(F)F)CC3=C2)=N1
Chemical Name

2-[(4S)-8-[2-[6-(Methylamino)pyridin-2-yl]ethoxy]-3-oxo-2-(2,2,2-trifluoroethyl)-4,5-dihydro-1H-2-benzazepin-4-yl]acetic acid

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Miller WH, et al. J Med Chem. 2000, 43(1), 22-26.

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