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(R)-Nepicastat HCl
CAS No. 195881-94-8
(R)-Nepicastat HCl( —— )
Catalog No. M17411 CAS No. 195881-94-8
(R)-Nepicastat HCl, the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 122 | Get Quote |
|
| 10MG | 206 | Get Quote |
|
| 25MG | 389 | Get Quote |
|
| 50MG | 527 | Get Quote |
|
| 100MG | 770 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product Name(R)-Nepicastat HCl
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NoteResearch use only, not for human use.
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Brief Description(R)-Nepicastat HCl, the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.
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Description(R)-Nepicastat HCl, the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorDopamine β-hydroxylase| Dopamine β-hydroxylase
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Research AreaCardiovascular Disease
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Indication——
Chemical Information
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CAS Number195881-94-8
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Formula Weight331.81
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Molecular FormulaC14H15F2N3S·HCl
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.NCC1=CNC(=S)N1[C@@H]1CCC2=C(F)C=C(F)C=C2C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Stanley WC, et al. Br J Pharmacol. 1997, 121(8), 1803-1809.
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